Alex Kentsis, MD, PhD
Year elected: 2018
Current membership category: Active
Memorial Sloan Kettering Cancer Center
1275 York Avenue
New York, NY 10065
United States of America
Alex Kentsis is a pediatric oncologist and cancer biologist. His research takes advantage of modern technologies to improve our understanding of the biologic causes of blood and solid tumors. Together with colleagues, he has made discoveries about new therapeutic targets in cancer cells, mechanisms by which cancer cells can evade new treatments, and improved strategies to overcome treatment resistance. Recently, his lab has identified new mechanisms of aberrant gene control and resistance to apoptosis in acute myeloid leukemias, and mechanisms of site-specific oncogenic mutations and DNA repair dependencies in solid tumors. This work is now poised to define precise molecular mechanisms that would lead to rational therapeutic strategies for patients.