Ryan B. Corcoran, MD, PhD
Year elected: 2017
Current membership category: Active
Massachusetts General Hospital
Building 149, Thirteenth Street
Charlestown, MA 02129
United States of America
Dr. Corcoran is the Director of the Gastrointestinal Cancer Center Program at the Massachusetts General Hospital Cancer Center and an Assistant Professor in Medicine at Harvard Medical School. Dr. Corcoran graduated from Princeton University with an AB in Molecular Biology and received an MD and a PhD in Cancer Biology from the Stanford University School of Medicine. He completed his residency training in Internal Medicine at the Massachusetts General Hospital and his fellowship training in Medical Oncology at the Dana-Farber Cancer Institute and the Massachusetts General Hospital Cancer Center.
Dr. Corcoran directs a research laboratory focused on personalized cancer medicine: the development of therapeutic strategies that target the specific mutations driving individual patients’ tumors. Dr. Corcoran’s efforts are directed towards patients with gastrointestinal cancers, including colorectal and pancreatic cancer, which are the second and fourth leading causes of cancer death in the United States, respectively, as well as esophagogastric cancer, the fastest growing cancer in the nation. His work focuses on understanding the molecular determinants of response or resistance to anti-cancer therapies. Dr. Corcoran’s laboratory is also pioneering new ways to utilize “Liquid Biopsy” analysis of circulating tumor DNA in the clinic to optimize how we deliver cancer care to individual patients. Through his continued translational work in these areas, Dr. Corcoran strives to integrate both laboratory and clinical research efforts to more rapidly develop new and effective treatments for patients suffering from these lethal cancers.