Aimee S. Payne, MD, PhD
Year elected: 2016
Current membership category: Active
University of Pennsylvania
421 Curie Blvd
1009 Curie Blvd
Philadelphia, PA 19104
United States of America
Phone: 215-746-4488

Biographical statement

Dr. Payne is an Associate Professor of Dermatology at the University of Pennsylvania. Her career interest has been in pemphigus: diagnosing and treating patients with this potentially fatal autoimmune disease, and performing research to better understand disease, with the goal of improving therapy.  Dr. Payne received her BS in Biology from Stanford University and her MD/PhD from Washington University School of Medicine, followed by residency and postdoctoral fellowship training in Dermatology at the University of Pennsylvania. Her research has focused on three major areas of investigation: 1) cloning and characterization of B cell repertoires to understand how autoimmunity occurs in pemphigus, which has discovered common features of the B cell response among patients; 2) cell biologic studies to identify mechanisms for loss of cell adhesion, which has identified the p38/MK2 axis as a key regulator of desmosome adhesion in keratinocytes; and 3) patient-oriented research to improve pemphigus therapy, which has led to a better understanding of B cell depletion strategies in pemphigus as well as novel  strategies for targeted therapy of disease.  Dr. Payne is active in the International Pemphigus and Pemphigoid Foundation patient group and is a member of an international committee of physicians that has developed consensus definitions and disease activity instruments for use in clinical trials. At Penn, Dr. Payne serves as Associate Director of the Medical Scientist Training Program and faculty advisor for the Association of Women Student MD-PhDs (AWSM), through which she enjoys interacting with the larger physician-scientist community.

Institutional affiliations

University of Pennsylvania Perelman School of Medicine (Primary)
Ben Z. Stanger, MD, PhD is the representative at this institution.