Timothy M. Miller, MD, PhD
Year elected: 2016
Current membership category: Active
Washington University School of Medicine
Department of Neurology
660 S. Euclid Ave., Box 8111
St. Louis, MO 63110
United States of America
Phone: 314-362-8169
Email: millert@neuro.wustl.edu

Biographical statement

My research group focuses on understanding and developing novel therapeutic strategies for neurodegenerative diseases, including amyotrophic lateral sclerosis and dementias related to the protein tau.   We have developed antisense oligonucleotide mRNA inhibitors for superoxide dismutase 1, miRNAs, and tau and have demonstrated that this approach improves pathology and behavior in animal models.  Antisense oligonucleotides targeting SOD1 have been evaluated in early phase clinical trial in participants with SOD1-related amyotrophic lateral sclerosis.

Institutional affiliations

Washington University School of Medicine in St. Louis (Primary)
Deborah J. Veis, MD, PhD is the representative at this institution.