Margaret Feeney, MD, MMSc
Year elected: 2016
Current membership category: Active
University of California, San Francisco
Division of Pediatric Infectious Diseases and Global Health
1001 Potrero Ave, Bldg 3, Rm 545A
San Francisco, CA 94110
United States of America
Phone: 415-206-8218
Email: margaret.feeney@ucsf.edu

Biographical statement

My research interests center on the immunopathogenesis of HIV and malaria in childhood. The broad goal of my research program is to identify correlates of protective immunity to these pathogens in order to guide the rational design of vaccines and immunomodulatory therapies. I am also interested in understanding how chronic infection triggers immunoregulatory mechanisms that interfere with pathogen clearance and the development of sterilizing immunity. My research group studies the human immune response to malaria in the context of large cohorts of naturally exposed individuals, primarily in eastern Uganda. As a pediatrician, I have a particular interest in infant immune development and how the immune response of infants differs from that of adults. Studies underway in my lab currently focus on the correlates of naturally acquired antimalarial immunity, the use of blood stage malaria chemoprevention to enhance the functional quality of plasmodium-specific CD4 T cells, and the impact of in utero malaria exposure on fetal tolerance induction and subsequent immunity. Lastly, we are investigating the role of gamma-delta T cells and other non-classical T cell populations in the immune response to malaria.

Institutional affiliations

University of California, San Francisco, School of Medicine (Primary)
Suneil K. Koliwad, MD, PhD is the representative at this institution.

Specialties

Immunology
Infectious Disease
Pediatrics
Vaccines