Derek W. Abbott, MD, PhD
Year elected: 2016
Current membership category: Active
Case Western Reserve University School of Medicine
Room 6531 Wolstein Research Building, 2103 Cornell Road
Cleveland, OH 44106
United States of America
My laboratory utilizes synthetic biology and chemical genetics to study innate immunity’s role in the pathogenesis of autoinflammatory disease. In particular, given phosphorylation and ubiquitination’s prominent role in innate immune signaling, we want to understand how these post-translational mechanisms go awry in autoinflammatory disease and whether this knowledge can be used for clinical gain.