Farouc Amin Jaffer, MD, PhD
Photo: Farouc Amin Jaffer

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Elected 2013

Dr. Farouc Jaffer graduated from Stanford University with a degree in Mathematical and Computational Sciences and received his M.D. and Ph.D. in Biophysics from the University of Pennsylvania School of Medicine in 1996. He was a Howard Hughes Medical Institute–NIH Research Scholar from 1993 to 1995. He then completed a residency in internal medicine at the Brigham and Women’s Hospital (1999) and then a fellowship in Cardiovascular Medicine and Interventional Cardiology at Massachusetts General Hospital (MGH), which included a postdoctoral research fellowship in the Center for Molecular Imaging Research (CMIR) at MGH. In 2003, Dr. Jaffer joined the MGH Cardiology Division as a faculty member. In 2012, he was promoted to Associate Professor of Medicine at Harvard Medical School.

Dr. Jaffer’s research is focused in three major areas: (1) understanding the role of in vivo inflammation in coronary atherosclerosis and in coronary stent healing, via the development of translatable intravascular near-infrared fluorescence (NIRF) imaging technology and reporter agents — Dr. Jaffer and his team have developed several new intravascular imaging approaches (NIRF, NIRF + IVUS hybrid imaging, and single-catheter OFDI + NIRF imaging) designed to illuminate molecular events in coronary-sized vessels; (2) investigation of the in vivo role of inflammation in atherogenesis and thrombus resolution using intravital microscopy; (3) development of optical molecular imaging agents for atherothrombosis, including reporters for macrophages, fibrin, cathepsin K, VCAM-1, thrombin, and activated factor XIII.