Photo: William M. Grady, MD
William M. Grady, MD
Year elected: 2009
Current membership category: Senior
Fred Hutchinson Cancer Research Center
1100 Fairview Ave. N.
Seattle, WA 98109
United States of America
Phone: 206-667-1107

Biographical statement

Dr. Grady's research has revealed the role of epigenetic and genetic alterations in the pathogenesis of colorectal cancer. He specifically has demonstrated that aberrant DNA methylation is involved in the initiation and progression of colorectal cancer and that mutational inactivation of the gene for the type II TGF-beta receptor drives the progression of colon adenomas to cancer. He has further demonstrated that aberrantly methylated genes can be used as biomarkers for the detection of colorectal cancer and adenomas.

Institutional affiliations

Fred Hutchinson Cancer Research Center (Primary)
University of Washington School of Medicine (Secondary)


Cancer biology
Internal Medicine
Molecular Biology
Translational Medicine

Positions held

Medical Director