Ming-Hui Zou, M.D. Ph.D. is the eminent scholar in Georgia Research Alliance in Georgia, USA. Dr. Zou is the founding director, the Center of Molecularand Translational Medicine, and the Associate Vice President for Research, Georgia State University. Before he joined the Georgia State University, Dr. Zou was the George Lynn Cross Professor and Warren Endowed Chair in Diabetes Research in the University of Oklahoma Health Science Center, the Chief of Section of Molecular Medicine, and Vice Chair for Research in the Department of Medicine from 2005-2015. Dr. Zou has been very productively working in the area of cardiovascular biology and diseases over 15 years. Means to sense oxidative stress, reduce it, or ameliorate the body’s adverse response to it are central to Dr. Zou’s ongoing research programs. Dr. Zou was instrumental in examining the role of nitric oxide and oxidative stress in the regulation of blood flow and vascular function. He performed elegant, state of the art, studies to show that the selective modification of two key proteins, rosptacyclin synthase and endothelial nitric oxide synthase, is critical in the dysregulation of vessel function from nitric oxide and superoxide. Dr. Zou’s group was also the first to demonstrate that the AMP-activated kinase (AMPK), a key enzyme in the regulation of energy metabolism, obesity, diabetes, and cardiovascular diseases, functions as a sensor and regulator of oxidative stress. Dr. Zou’s contributions in this area are important and his work represents outstanding breakthroughs research which has been recognized by many other investigators in the fields. An independent investigator of the National Institutes of Health and the Juvenile Diabetes Research Foundation International (JDRF) and a National Scientist Development awardee of the American Heart Association, Dr. Zou has used these (and many other awards) to make scientific observations in fields with great potential for immediate clinical relevance. He has served on several national study panels such as the National Institutes of Health and American Heart Association. In 2008 he was elected to the American Society for Clinical Investigation, one of the US’ oldest honor societies of physician-scientists, membership in which reflects accomplishments by its members at an early stage in their careers.