Dr. Moe is the Vice Chair for Research in the Department of Medicine at Indiana University School of Medicine. Dr. Moe received her medical degree from the University of Illinois College of Medicine at Chicago. She completed her internship and residency in the Department of Internal Medicine at Loyola University Medical Center in Maywood, Illinois. Her research and clinical fellowships were completed in the Section of Nephrology of the Department of Medicine at the University of Chicago in Illinois. She has been a faculty member at Indiana University since 1992.

Dr. Moe’s research interests are in disorders of bone and mineral metabolism in patients with chronic kidney disease, specifically renal osteodystrophy and vascular calcification and the relationship between the two diseases. She has examined the pathogenesis of vascular calcification in vivo and in vitro, determining that in dialysis patients vascular calcification is a cell mediated process, with de-differentiation of vascular smooth muscle cells to an osteoblast phenotype. This appears to be mediated by upregulation of the “osteoblast” transcription factor core binding factor alpha 1 (Cbfa1) as expression of Cbfa1 is upregulated by in situ hybridization in calcified arteries in dialysis patients, and in cultured vascular smooth muscle cells in response to pooled serum from dialysis patients. She is also working on the role of fetuin-A, a naturally occurring inhibitor of mineralization in the pathogenesis of vascular calcification. Dr. Moe has investigated the use of spiral CT for the assessment of coronary artery calcification in dialysis patients and transplant recipients. In addition, Dr. Moe has been actively involved in new treatments for renal osteodystrophy in patients with chronic kidney disease including novel phosphate binders, different forms of vitamin D and calcimimetics.